A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People with Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Trial Identifier: 2140-011
Sponsor: MSD
Start Date: April 2025
Primary Completion Date: December 2027
Study Completion Date: December 2032

Available Languages

For questions about your Trial Results Summary, please see Sponsor contact section within your Trial Results Summary.

Language Description
Protocol Plain Language Summary

Trial Locations

Country Location
Belgium, Antwerpen Mechelen, Antwerpen, Belgium, 2800
Belgium, Brabant wallon Mons, Brabant wallon, Belgium, 7000
Belgium, Bruxelles-Capitale, Region de Brussels, Bruxelles-Capitale, Region de, Belgium, 1200
Belgium, Oost-Vlaanderen Sint-Niklaas, Oost-Vlaanderen, Belgium, 9100
Belgium, Vlaams-Brabant Leuven, Vlaams-Brabant, Belgium, 3000
Belgium, West-Vlaanderen Roeselare, West-Vlaanderen, Belgium, 8800
Germany, Baden-Wurttemberg Stuttgart, Baden-Wurttemberg, Germany, 70174
Germany, Bayern Erlangen, Bayern, Germany, 91054
Germany, Bayern Wuerzburg, Bayern, Germany, 97080
Germany, Hessen Frankfurt, Hessen, Germany, 60389
Germany, Mecklenburg-Vorpommern Neubrandenburg, Mecklenburg-Vorpommern, Germany, 17036
Germany, Niedersachsen Hannover, Niedersachsen, Germany, 30459
Germany, Nordrhein-Westfalen Wuppertal, Nordrhein-Westfalen, Germany, 42283
Germany, Sachsen Chemnitz, Sachsen, Germany, 09113
Germany, Sachsen-Anhalt Magdeburg, Sachsen-Anhalt, Germany, 39120
Germany, Schleswig-Holstein Lubeck, Schleswig-Holstein, Germany, 23562
Germany, Thuringen Jena, Thuringen, Germany, 07747
Ireland, Dublin Dublin, Ireland, D07 R2WY
Ireland, Dublin Dublin 04, Dublin, Ireland, D04 T6F4
Ireland, Limerick Limerick, Ireland, V94 F858
Israel, N/A Beer Sheva, N/A, Israel, 8410101
Israel, N/A Haifa, N/A, Israel, 3109601
Israel, N/A Holon, N/A, Israel, 5810001
Israel, N/A Jerusalem, N/A, Israel, 9112001
Israel, N/A Petah Tikva, N/A, Israel, 4941492
Israel, N/A Ramat Gan, N/A, Israel, 5265601
Israel, N/A Safed, N/A, Israel, 13100
Israel, N/A Tel Aviv, N/A, Israel, 6423906
Italy, Alessandria Alessandria, Italy, 15121
Italy, Forli-Cesena Meldola, Forli-Cesena, Italy, 47014
Italy, Milano Milano, Italy, 20141
Italy, Milano Rozzano, Milano, Italy, 20089
Italy, Napoli Napoli, Italy, 80131
Italy, Palermo PALERMO, Palermo, Italy, 90146
Italy, Reggio Emilia Reggio Emilia, Italy, 42123
Japan, Aichi Nagoya, Aichi, Japan, 464-8681
Japan, Aichi Toyoake, Aichi, Japan, 470-1192
Japan, Hokkaido Sapporo, Hokkaido, Japan, 060-8648
Japan, Miyagi Sendai, Miyagi, Japan, 983-8520
Japan, Nagasaki Nagasaki, Japan, 852-8501
Japan, Osaka Hirakata, Osaka, Japan, 573-1191
Japan, Shimane Izumo, Shimane, Japan, 693-8501
Japan, Tokyo Bunkyo, Tokyo, Japan, 113-8603
Japan, Tokyo Chuo, Tokyo, Japan, 104-0045
Poland, Dolnoslaskie Walbrzych, Dolnoslaskie, Poland, 58-309
Poland, Malopolskie Karkow, Malopolskie, Poland, 30-727
Poland, Malopolskie Nowy Sącz, Malopolskie, Poland, 33-300
Poland, Mazowieckie Warszawa, Mazowieckie, Poland, 02-781
Poland, Pomorskie Gdansk, Pomorskie, Poland, 80-214
Poland, Slaskie Katowice, Slaskie, Poland, 40-519
United Kingdom, Birmingham Birmingham, United Kingdom, B15 2TH
United Kingdom, Bristol, City of Bristol, Bristol, City of, United Kingdom, BS2 8ED
United Kingdom, Buckinghamshire Aylesbury, Buckinghamshire, United Kingdom, HP21 8AL
United Kingdom, Devon Exeter, Devon, United Kingdom, EX2 5DW
United Kingdom, Devon Plymouth, Devon, United Kingdom, PL68DH
United Kingdom, England Middlesbrough, England, United Kingdom, TS4 3BW
United Kingdom, Lincolnshire Lincoln, Lincolnshire, United Kingdom, LN2 5QY
United Kingdom, Liverpool Liverpool, United Kingdom, L7 8YA
United Kingdom, London, City of London, London, City of, United Kingdom, W12 0 HS
United Kingdom, London, City of London, London, City of, United Kingdom, SE1 9RT
United Kingdom, Manchester Manchester, United Kingdom, M20 4BX
United Kingdom, Oxfordshire Oxford, Oxfordshire, United Kingdom, OX3 7LJ
United States, AL Mobile, AL, United States, 36607
United States, AR Hot Springs, AR, United States, 71913
United States, AZ Chandler, AZ, United States, 85224
United States, AZ Glendale, AZ, United States, 85304
United States, AZ Goodyear, AZ, United States, 85338
United States, CA Burbank, CA, United States, 91505
United States, CA Duarte, CA, United States, 91010
United States, CA Walnut Creek, CA, United States, 94598
United States, CO Aurora, CO, United States, 80012
United States, CO Grand Junction, CO, United States, 81505
United States, DC Washington, DC, United States, 20007
United States, DE Newark, DE, United States, 19713
United States, FL Boca Raton, FL, United States, 33486
United States, FL Jacksonville, FL, United States, 32207
United States, FL Miami Beach, FL, United States, 33140
United States, FL Orange City, FL, United States, 32763
United States, IA Iowa City, IA, United States, 52242
United States, IA Waukee, IA, United States, 50263
United States, ID Post Falls, ID, United States, 83854
United States, IL Chicago, IL, United States, 60637
United States, IL Peoria, IL, United States, 61615
United States, KY Edgewood, KY, United States, 41017
United States, KY Elizabethtown, KY, United States, 42701
United States, KY Lexington, KY, United States, 40503
United States, KY Louisville, KY, United States, 40207
United States, LA Baton Rouge, LA, United States, 70808
United States, LA Monroe, LA, United States, 71202
United States, LA New Orleans, LA, United States, 70121
United States, LA Shreveport, LA, United States, 71103
United States, MA Boston, MA, United States, 02215
United States, MN Burnsville, MN, United States, 55337
United States, MT Bozeman, MT, United States, 59715
United States, NC Chapel Hill, NC, United States, 27514
United States, NC Charlotte, NC, United States, 28204
United States, NC Winston-Salem, NC, United States, 27103
United States, NE Lincoln, NE, United States, 68506
United States, NE Omaha, NE, United States, 68198
United States, NJ Morristown, NJ, United States, 07960
United States, NJ Paramus, NJ, United States, 07652
United States, NY Buffalo, NY, United States, 14215
United States, NY Buffalo, NY, United States, 14263
United States, NY Mineola, NY, United States, 11501
United States, NY New York, NY, United States, 10016
United States, NY Syracuse, NY, United States, 13210
United States, NY Westbury, NY, United States, 11590
United States, OH Cincinnati, OH, United States, 45219
United States, OH Cleveland, OH, United States, 44195
United States, OH Cleveland, OH, United States, 44111
United States, OH Cleveland, OH, United States, 44106
United States, OH Mayfield Heights, OH, United States, 44124
United States, OR Portland, OR, United States, 97213
United States, OR Portland, OR, United States, 97225
United States, PA Philadelphia, PA, United States, 19140
United States, PA Sellersville, PA, United States, 18960
United States, PA York, PA, United States, 17403
United States, SC Charleston, SC, United States, 29425
United States, TN Knoxville, TN, United States, 37909
United States, TN Nashville, TN, United States, 37203
United States, TX Amarillo, TX, United States, 79124
United States, TX Austin, TX, United States, 78705
United States, TX Palestine, TX, United States, 75801
United States, TX San Antonio, TX, United States, 78240
United States, TX Tyler, TX, United States, 75701
United States, UT Murray, UT, United States, 84107
United States, UT Saint George, UT, United States, 84790
United States, VA Manassas, VA, United States, 20110
United States, VA Richmond, VA, United States, 23219
United States, WA Vancouver, WA, United States, 98684
United States, WI Madison, WI, United States, 53715
United States, WI Milwaukee, WI, United States, 53226