Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)

Trial Identifier: 5684-003
Sponsor: MSD
Collaborator:
Orion Corporation
Start Date: December 2023
Primary Completion Date: August 2028
Study Completion Date: August 2028

Available Languages

For questions about your Trial Results Summary, please see Sponsor contact section within your Trial Results Summary.

Language Description
Protocol Plain Language Summary

Trial Locations

Country Location
Argentina, Buenos Aires Buenos Aires, Argentina, C1118AAT
Argentina, Buenos Aires Ciudad autónoma de Buenos Aires, Buenos Aires, Argentina, C1280AEB
Argentina, Buenos Aires Mar del Plata, Buenos Aires, Argentina, B7600FZO
Argentina, CABA Buenos Aires, CABA, Argentina, C1419AHN
Argentina, CABA Ciudad Autónoma de Buenos Aires, CABA, Argentina, 1426ANZ
Argentina, Mendoza Mendoza, Argentina, M5500AYB
Argentina, Santa Fe Rosario, Santa Fe, Argentina, S2000DVC
Australia, New South Wales Dubbo, New South Wales, Australia, 2830
Australia, New South Wales Macquarie University, New South Wales, Australia, 2109
Australia, New South Wales Westmead, New South Wales, Australia, 2145
Australia, Queensland Brisbane, Queensland, Australia, 4102
Australia, Victoria Melbourne, Victoria, Australia, 3000
Austria, Oberosterreich Linz, Oberosterreich, Austria, 4020
Austria, Oberosterreich Wels, Oberosterreich, Austria, 4600
Austria, Steiermark Graz, Steiermark, Austria, 8036
Brazil, Bahia Salvador, Bahia, Brazil, 40415-006
Brazil, Espirito Santo Vitoria, Espirito Santo, Brazil, 29041-295
Brazil, Minas Gerais Belo Horizonte, Minas Gerais, Brazil, 30380-472
Brazil, Minas Gerais Belo Horizonte, Minas Gerais, Brazil, 30110-934
Brazil, Parana Curitiba, Parana, Brazil, 80440-220
Brazil, Santa Catarina Itajai, Santa Catarina, Brazil, 88301-220
Brazil, Sao Paulo Bragança Paulista, Sao Paulo, Brazil, 12916-542
Brazil, Sao Paulo São Paulo, Sao Paulo, Brazil, 01509-010
Canada, AB Edmonton, AB, Canada, T6G 1Z2
Canada, ON Ottawa, ON, Canada, K1H 8L6
Canada, ON Toronto, ON, Canada, M4N 3M5
Canada, ON Toronto, ON, Canada, M5G 2M9
Canada, QC Greenfield Park, QC, Canada, J4V 2H1
Canada, QC Montréal, QC, Canada, H2X 3E4
Canada, QC Quebec City, QC, Canada, G1J 1Z4
Canada, QC Sherbrooke, QC, Canada, J1H 5H4
Chile, Antofagasta Antofagasta, Chile, 1240000
Chile, Coquimbo La Serena., Coquimbo, Chile, 1720430
Chile, Los Rios Valdivia, Los Rios, Chile, 5110683
Chile, Maule Talca, Maule, Chile, 3465584
Chile, Region M. de Santiago Santiago, Region M. de Santiago, Chile, 8420383
Chile, Region M. de Santiago Santiago, Region M. de Santiago, Chile, 7500921
Chile, Region M. de Santiago Santiago, Region M. de Santiago, Chile, 8330024
China, Anhui Hefei, Anhui, China, 230000
China, Beijing Beijing, China, 100034
China, Beijing Beijing, China, 100142
China, Beijing Beijing, China, 100050
China, Chongqing Chongqing, China, 400038
China, Chongqing Chongqing, China, 404100
China, Chongqing Chongqing, China, 400010
China, Chongqing Chongqing, China, 400030
China, Fujian Fuzhou, Fujian, China, 350005
China, Fujian Xiamen, Fujian, China, 361003
China, Guangdong Guangzhou, Guangdong, China, 511400
China, Guangdong Guangzhou, Guangdong, China, 510120
China, Hubei Wuhan, Hubei, China, 430079
China, Hubei Wuhan, Hubei, China, 430000
China, Hunan Changsha, Hunan, China, 410013
China, Jiangsu Huaian, Jiangsu, China, 223300
China, Jiangsu NanJing, Jiangsu, China, 210008
China, Jiangsu Wuxi, Jiangsu, China, 214122
China, Jiangxi Nanchang, Jiangxi, China, 330029
China, Shaanxi Xi an, Shaanxi, China, 710004
China, Shaanxi xi'an, Shaanxi, China, 710061
China, Shandong Yantai, Shandong, China, 264099
China, Shangai Shangai, China, 200032
China, Shanghai Shanghai, China, 200041
China, Shanghai Shanghai, China, 200000
China, Sichuan Cheng Du, Sichuan, China, 610041
China, Sichuan Chengdu, Sichuan, China, 500643
China, Sichuan Nanchong, Sichuan, China, 500643
China, Sichuan Suining, Sichuan, China, 629000
China, Tianjin Tianjin, China, 300211
China, Tianjin Tianjin, China, 300060
China, Xinjiang Urumqi, Xinjiang, China, 830000
China, Yunnan Kunming, Yunnan, China, 650033
China, Yunnan Kunming, Yunnan, China, 650107
China, Zhejiang Hangzhou, Zhejiang, China, 310014
China, Zhejiang Hangzhou, Zhejiang, China, 310022
China, Zhejiang Jiaxing, Zhejiang, China, 314001
China, Zhejiang Ningbo, Zhejiang, China, 315010
China, Zhejiang Wenzhou, Zhejiang, China, 325000
Colombia, Cesar Valledupar, Cesar, Colombia, 200001
Colombia, Cordoba Monteria, Cordoba, Colombia, 230002
Colombia, Distrito Capital de Bogota Bogota, Distrito Capital de Bogota, Colombia, 111321
Colombia, Santander Piedecuesta, Santander, Colombia, 681017
Colombia, Valle del Cauca Cali, Valle del Cauca, Colombia, 760032
Colombia, Valle del Cauca Cali, Valle del Cauca, Colombia, 760042
Czech Republic, Brno-mesto Brno, Brno-mesto, Czech Republic, 656 53
Czech Republic, Moravskoslezsky kraj Ostrava, Moravskoslezsky kraj, Czech Republic, 708 52
Czech Republic, Olomoucky kraj Olomouc, Olomoucky kraj, Czech Republic, 779 00
Czech Republic, Praha 5 Praha, Praha 5, Czech Republic, 150 06
Denmark, Hovedstaden Copenhagen, Hovedstaden, Denmark, 2100
Denmark, Syddanmark Odense, Syddanmark, Denmark, 5000
Denmark, Syddanmark Vejle, Syddanmark, Denmark, 7100
Finland, Pirkanmaa Tampere, Pirkanmaa, Finland, 33520
Finland, Pohjois-Savo Kuopio, Pohjois-Savo, Finland, 70210
Finland, Varsinais-Suomi Turku, Varsinais-Suomi, Finland, 20520
France, Alsace Strasbourg, Alsace, France, 67200
France, Gard Nîmes, Gard, France, 30029
France, Ille-et-Vilaine Rennes, Ille-et-Vilaine, France, 35042
France, Paris Paris, France, 75015
France, Puy-de-Dome Clermont-Ferrand, Puy-de-Dome, France, 63003
France, Pyrenees-Atlantiques Bayonne, Pyrenees-Atlantiques, France, 64109
France, Val-de-Marne villejuif, Val-de-Marne, France, 94800
Germany, Bayern Munich, Bayern, Germany, 81675
Germany, Berlin Berlin, Germany, 10117
Germany, Hamburg Hamburg, Germany, 20246
Germany, Mecklenburg-Vorpommern Schwerin, Mecklenburg-Vorpommern, Germany, 19055
Germany, Nordrhein-Westfalen Bonn, Nordrhein-Westfalen, Germany, 53127
Germany, Nordrhein-Westfalen Münster, Nordrhein-Westfalen, Germany, 48149
Germany, Schleswig-Holstein Lubeck, Schleswig-Holstein, Germany, 23538
Germany, Thuringen Jena, Thuringen, Germany, 07747
Hong Kong, N/A Hong Kong, N/A, Hong Kong, N/A
Hong Kong, N/A Shatin, N/A, Hong Kong, NA
Hungary, Bacs-Kiskun Kecskemét, Bacs-Kiskun, Hungary, 6000
Hungary, Debrecen Debrecen, Hungary, 4032
Hungary, Nograd Salgótarján, Nograd, Hungary, 3100
Hungary, Pest Budapest, Pest, Hungary, 1122
Ireland, Dublin Dublin, Ireland, D24 NR0A
Ireland, Dublin Dublin 04, Dublin, Ireland, D04 T6F4
Israel, N/A Afula, N/A, Israel, 1834111
Israel, N/A Haifa, N/A, Israel, 3109601
Israel, N/A Jerusalem, N/A, Israel, 9112001
Israel, N/A Kfar Saba, N/A, Israel, 4428164
Israel, N/A Petah Tikva, N/A, Israel, 4941492
Israel, N/A Ramat Gan, N/A, Israel, 5265601
Italy, Emilia-Romagna Meldola, Emilia-Romagna, Italy, 47014
Italy, Lombardia Milan, Lombardia, Italy, 20133
Italy, Milano Milano, Italy, 20132
Japan, Akita Akita, Japan, 010-8543
Japan, Chiba Sakura, Chiba, Japan, 285-8741
Japan, Ehime Toon, Ehime, Japan, 791-0295
Japan, Fukuoka Fukuoka, Japan, 812-8582
Japan, Fukuoka Kitakyushu, Fukuoka, Japan, 807-8556
Japan, Fukuoka Kurume, Fukuoka, Japan, 830-0011
Japan, Fukushima Fukushima, Japan, 960-1295
Japan, Gifu Gifu, Japan, 501-1112
Japan, Hiroshima Hiroshima, Japan, 734-8551
Japan, Hokkaido Asahikawa, Hokkaido, Japan, 078-8510
Japan, Hokkaido Sapporo, Hokkaido, Japan, 060-8543
Japan, Hokkaido Sapporo, Hokkaido, Japan, 060-8648
Japan, Hyogo Kobe, Hyogo, Japan, 650-0017
Japan, Ishikawa Uchinada, Ishikawa, Japan, 920-0265
Japan, Kagawa Kita, Kagawa, Japan, 761-0701
Japan, Kagoshima Kagoshima, Japan, 890-8520
Japan, Kanagawa Yokohama, Kanagawa, Japan, 232-0024
Japan, Kumamoto Kumamoto, Japan, 860-0008
Japan, Miyazaki Miyazaki, Japan, 880-8510
Japan, Miyazaki Miyazaki, Japan, 889-1692
Japan, Nagano Nagano, Japan, 381-8551
Japan, Nagasaki Ōmura, Nagasaki, Japan, 856-8562
Japan, Nara Kashihara, Nara, Japan, 634-8522
Japan, Oita Oita, Japan, 870-0263
Japan, Okinawa Shimajiri, Okinawa, Japan, 901-0417
Japan, Osaka Hirakata, Osaka, Japan, 573-1191
Japan, Osaka Sakai, Osaka, Japan, 599-8247
Japan, Osaka Suita, Osaka, Japan, 565-0871
Japan, Saga Saga-shi, Saga, Japan, 840-8571
Japan, Tokyo Minato, Tokyo, Japan, 105-8471
Korea, Republic of, Seoul Seoul, Korea, Republic of, 03080
Korea, Republic of, Seoul Seoul, Korea, Republic of, 03722
Korea, Republic of, Seoul Seoul, Korea, Republic of, 06351
Korea, Republic of, Seoul Songpagu, Seoul, Korea, Republic of, 05505
Malaysia, Johor Johor Bahru, Johor, Malaysia, 81100
Malaysia, Kuala Lumpur Kuala Lumpur, Malaysia, 50586
Malaysia, Kuala Lumpur Lembah Pantai, Kuala Lumpur, Malaysia, 59100
Malaysia, Sarawak Kuching, Sarawak, Malaysia, 93586
Malaysia, Wilayah Persekutuan Putrajaya PUTRAJAYA, Wilayah Persekutuan Putrajaya, Malaysia, 62250
Mexico, Distrito Federal Mexico City, Distrito Federal, Mexico, 14308
Mexico, Jalisco Guadalajara, Jalisco, Mexico, 44630
Mexico, Nuevo Leon Monterrey, Nuevo Leon, Mexico, 64460
Mexico, Oaxaca Oaxaca, Mexico, 68020
Mexico, Yucatan Merida, Yucatan, Mexico, 97070
Netherlands, Fryslan Leeuwarden, Fryslan, Netherlands, 8934 AD
Netherlands, Gelderland Nijmegen, Gelderland, Netherlands, 6525 GA
Netherlands, Limburg Sittard-Geleen, Limburg, Netherlands, 6162 BG
Netherlands, Limburg Venlo, Limburg, Netherlands, 5912 BL
Netherlands, Noord-Brabant Tilburg, Noord-Brabant, Netherlands, 5022 GC
Netherlands, Noord-Holland Amsterdam, Noord-Holland, Netherlands, 1066 CX
Netherlands, Noord-Holland Amsterdam, Noord-Holland, Netherlands, 1081 HV
Netherlands, Noord-Holland Hoofddorp, Noord-Holland, Netherlands, 2134 TM
Netherlands, Utrecht Amersfoort, Utrecht, Netherlands, 3813TZ
Netherlands, Zuid-Holland Den Haag, Zuid-Holland, Netherlands, 2545 AA
Netherlands, Zuid-Holland Schiedam, Zuid-Holland, Netherlands, 3118 JH
New Zealand, Bay of Plenty Tauranga, Bay of Plenty, New Zealand, 3112
New Zealand, Otago Dunedin, Otago, New Zealand, 9016
Norway, Akershus Lørenskog, Akershus, Norway, 1474
Norway, Ostfold Sarpsborg, Ostfold, Norway, 1714
Norway, Sor-Trondelag Trondheim, Sor-Trondelag, Norway, 7030
Peru, Junin Concepcion, Junin, Peru, 12125
Peru, La Libertad Trujillo, La Libertad, Peru, 13009
Peru, Lima Lima, Peru, 15036
Peru, Lima LIMA, Lima, Peru, 15038
Poland, Kujawsko-pomorskie Bydgoszcz, Kujawsko-pomorskie, Poland, 85-796
Poland, Kujawsko-pomorskie Grudziadz, Kujawsko-pomorskie, Poland, 86-300
Poland, Kujawsko-pomorskie Torun, Kujawsko-pomorskie, Poland, 87-100
Poland, Mazowieckie Siedlce, Mazowieckie, Poland, 08-110
Poland, Swietokrzyskie Kielce, Swietokrzyskie, Poland, 25-734
Poland, Zachodniopomorskie Koszalin, Zachodniopomorskie, Poland, 75-581
Poland, Zachodniopomorskie Szczecin, Zachodniopomorskie, Poland, 71-730
Singapore, Central Singapore Singapore, Central Singapore, Singapore, 168583
Singapore, Central Singapore Singapore, Central Singapore, Singapore, 308433
Singapore, Central Singapore Singapore, Central Singapore, Singapore, 119074
Spain, Cadiz Jerez de la Frontera, Cadiz, Spain, 11407
Spain, Lugo Lugo, Spain, 27003
Spain, Madrid, Comunidad de Madrid, Madrid, Comunidad de, Spain, 28034
Spain, Madrid, Comunidad de Madrid, Madrid, Comunidad de, Spain, 28041
Spain, Orense Ourense, Orense, Spain, 32005
Spain, Sevilla SEVILLA, Sevilla, Spain, 41013
Spain, Valenciana, Comunitat Valencia, Valenciana, Comunitat, Spain, 46009
Sweden, Stockholms lan Stockholm, Stockholms lan, Sweden, 171 64
Sweden, Uppsala lan Uppsala, Uppsala lan, Sweden, 751 85
Sweden, Vastra Gotalands lan Gothenburg, Vastra Gotalands lan, Sweden, 413 45
Taiwan, Taichung Taichung, Taiwan, 40447
Taiwan, Tainan TAINAN, Tainan, Taiwan, 704
Taiwan, Taipei Taipei, Taiwan, 112
Taiwan, Taipei Taipei, Taiwan, 10002
Taiwan, Taoyuan Taoyuan, Taiwan, 333
Thailand, Khon Kaen Muang, Khon Kaen, Thailand, 40002
Thailand, Krung Thep Maha Nakhon Bangkok, Krung Thep Maha Nakhon, Thailand, 10330
Thailand, Krung Thep Maha Nakhon Bangkok, Krung Thep Maha Nakhon, Thailand, 10700
Thailand, Songkhla hatyai, Songkhla, Thailand, 90110
Turkey, Adana Adana, Turkey, 01250
Turkey, Ankara Ankara, Turkey, 06520
Turkey, Ankara Ankara, Turkey, 06230
Turkey, Ankara Ankara, Turkey, 06800
Turkey, Ankara Ankara, Turkey, 06010
Turkey, Istanbul Istanbul, Turkey, 34722
Turkey, Istanbul Istanbul, Turkey, 34668
Turkey, Samsun Samsun, Turkey, 55200
United Kingdom, Cambridgeshire Cambridge, Cambridgeshire, United Kingdom, CB2 2QQ
United Kingdom, England Truro, England, United Kingdom, TR1 3LJ
United Kingdom, Glasgow City Glasgow, Glasgow City, United Kingdom, G12 0YN
United Kingdom, Hammersmith and Fulham london, Hammersmith and Fulham, United Kingdom, W6 8RF
United Kingdom, London, City of London, London, City of, United Kingdom, NW1 2PG
United Kingdom, Manchester manchester, Manchester, United Kingdom, m20 4bx
United States, CA Orange, CA, United States, 92868
United States, CA Palo Alto, CA, United States, 94304
United States, CA Riverside, CA, United States, 92505
United States, CO Aurora, CO, United States, 80045
United States, CO Highlands Ranch, CO, United States, 80129
United States, CO Lakewood, CO, United States, 80228
United States, CO Lone Tree, CO, United States, 80124
United States, CT New Haven, CT, United States, 06510
United States, FL Fort Myers, FL, United States, 33901
United States, FL Miami, FL, United States, 33136
United States, FL Miami, FL, United States, 33125
United States, IA Iowa City, IA, United States, 52242
United States, IL Chicago, IL, United States, 60612
United States, IL Chicago, IL, United States, 60637
United States, KY Lexington, KY, United States, 40536
United States, LA New Orleans, LA, United States, 70121
United States, MD Baltimore, MD, United States, 21201
United States, MI Detroit, MI, United States, 48202
United States, MN Minneapolis, MN, United States, 55455
United States, MN St. Louis Park, MN, United States, 55416
United States, MO St. Louis, MO, United States, 63110
United States, NE Omaha, NE, United States, 68105
United States, NJ Morristown, NJ, United States, 07960
United States, NJ New Brunswick, NJ, United States, 08901
United States, NV Las Vegas, NV, United States, 89148
United States, NY Bronx, NY, United States, 10468
United States, OH Cleveland, OH, United States, 44106
United States, OR Portland, OR, United States, 97239
United States, PA Pittsburgh, PA, United States, 15212
United States, PR Hato Rey, PR, United States, 00917
United States, PR Ponce, PR, United States, 00717
United States, PR San Juan, PR, United States, 00909
United States, SC Charleston, SC, United States, 29401
United States, SD Pierre, SD, United States, 57501
United States, SD Sioux Falls, SD, United States, 57105
United States, SD Yankton, SD, United States, 57078
United States, TN Nashville, TN, United States, 37203
United States, TX Austin, TX, United States, 78731
United States, TX Dallas, TX, United States, 75246
United States, TX The Woodlands, TX, United States, 77380
United States, VA Charlottesville, VA, United States, 22908
United States, VA Richmond, VA, United States, 23219
United States, VA Roanoke, VA, United States, 24014
United States, WA Seattle, WA, United States, 98109
United States, WI MILWAUKEE, WI, United States, 53226